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  4. Section 13
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Guide for Aviation Medical Examiners
  1. Front Matter
  2. Section 1: GENERAL INFORMATION
  3. Section 2: APPLICATION FOR MEDICAL CERTIFICATION
  4. Section 3: EXAMINATION TECHNIQUES
  5. Section 4: AME PHYSICAL EXAMINATION INFORMATION AND DISPOSITION TABLES
  6. Section 5: ITEMS 31-34. Eye
  7. Section 6: ITEM 35. Lungs and Chest
  8. Section 7: ITEM 36. Heart
  9. Section 8: ITEM 37. Vascular System
  10. Section 9: ITEM 38. Abdomen and Viscera
  11. Section 10: ITEM 39. Anus
  12. Section 11: ITEM 40. Skin
  13. Section 12: ITEM 41. G-U System
  14. Section 13: ITEMS 42-43. Musculoskeletal
    1. OSTEOMYELITIS (BONE INFECTION)
  15. Section 14: ITEM 44. Identifying Body Marks, Scars, Tattoos
  16. Section 15: ITEM 45. Lymphatics
  17. Section 16: ITEM 46. Neurologic
  18. Section 17: ITEM 47. Psychiatric
  19. Section 18: ITEM 48. General Systemic
  20. Section 19: AME OFFICE-REQUIRED ANCILLARY TESTING
  21. Section 20: AMCS SUPPORT DESK
  22. Section 21: APPLICATION REVIEW
  23. Section 22: CACI CONDITIONS
  24. Section 23: DISEASE PROTOCOLS
  25. Section 24: PHARMACEUTICALS
  26. Section 25: AME ASSISTED SPECIAL ISSUANCES (AASI)
  27. Section 26: SUBSTANCES OF DEPENDENCE/ABUSE
  28. Section 27: Drug/Alcohol Monitoring Programs and HIMS
  29. Section 28: SYNOPSIS OF MEDICAL STANDARDS
  30. Section 29: Student Pilot Rule Change
  31. Section 30: GLOSSARY
  32. Section 31: ARCHIVES AND UPDATES

Guide for Aviation Medical Examiners|Version 09/30/2026

Section 13

ITEMS 42-43. Musculoskeletal

13 pages|Pages 276–288

Read Citation (on FlightPush)
CHECK EACH ITEM IN APPROPRIATE COLUMNNormalAbnormal
42. Upper and lower extremities (Strength and range of motion)
43. Spine, other musculoskeletal

I. Code of Federal Regulations

All Classes: 14 CFR 67.113 (b)(c), 67.213 (b)(c), and 67.313 (b)(c)

(b) No other organic, functional, or structural disease, defect, or limitation that the Federal Air Surgeon, based on the case history and appropriate, qualified medical judgment relating to the condition involved finds -

(1)

Makes the person unable to safely perform the duties or exercise the privileges of the airman certificate applied for or held; or

(2)

May reasonably be expected, for the maximum duration of the airman medical certificate applied for or held, to make the person unable to perform those duties or exercise those privileges.

(c)

No medication or other treatment that the Federal Air Surgeon, based on the case history and appropriate, qualified medical judgment relating to the medication or other treatment involved, finds -

(1)

Makes the person unable to safely perform the duties or exercise the privileges of the airman certificate applied for or held; or

(2)

May reasonably be expected, for the maximum duration of the airman medical certificate applied for or held, to make the person unable to perform those duties or exercise those privileges.

II. Examination Techniques

Standard examination procedures should be used to make a gross evaluation of the integrity of the applicant's musculoskeletal system. The AME should note:

1.

Pain - neuralgia, myalgia, paresthesia, and related circulatory and neurological findings

2.

Weakness - local or generalized; degree and amount of functional loss

3.

Paralysis - atrophy, contractures, and related dysfunctions

4.

Motion coordination, tremors, loss or restriction of joint motions, and performance degradation

5.

Deformity - extent and cause

6.

Amputation - level, stump healing, and phantom pain

7.

Prostheses - comfort and ability to use effectively

III. Aerospace Medical Disposition

The following is a table that lists the most common conditions of aeromedical significance, and course of action that should be taken by the AME as defined by the protocol and disposition in the table. Medical certificates must not be issued to an applicant with medical conditions that require deferral, or for any condition not listed in the table that may result in sudden or subtle incapacitation without consulting the AMCD or the RFS. Medical documentation must be submitted for any condition in order to support an issuance of an airman medical certificate.

ITEM 42. Upper and Lower Extremities NEUROPATHY (Peripheral Neuropathy) All Classes

(Updated 01/25/2023)

DISEASE/CONDITIONEVALUATION DATADISPOSITION
A. NeuropathyWithout functional limitationsIf the AME can determine the condition is:• Under control;• Medications are acceptable; and• The individual has no symptoms that would interfere with flight duties:Symbol: A. Neuropathy
Without functional limitationsISSUEAnnotate this information in Block 60.If no AME explanation, the pilot may be asked to provide documentation.
B. NeuropathyWith weakness/ numbnessORFunctional limitationsSubmit the following for FAA review:1. A current, detailed Clinical Progress Note generated from a clinic visit with the treating physician no more than 90 days before the AME exam. It must include a detailed summary of the neuropathy (including etiology if known); current medications, dosage, and side effects (if any); physical exam findings; results of any testing performed; diagnosis; assessment and plan (prognosis); and follow-up.2. It must specifically include a description of any weakness, numbness, or functional limitations.3. Lab already performed for this condition.4. Any other testing or imaging deemed clinically necessary by the treating physician.Note: If the neuropathy is due to an underlying condition such as diabetes - see that section.Symbol: B. Neuropathy
With weakness/ numbness
OR
Functional limitationsDEFERSubmit the information to the FAA for a possible Special Issuance Annotate (elements or findings) in Block 60.If not addressed in the progress note, the AME should describe any functional limitations that could affect the pilot's ability to operation aircraft controls.

OSTEOMYELITIS (BONE INFECTION)

  • All Classes
  • Updated 08/26/2026
DISEASE/CONDITIONEVALUATION DATADISPOSITION
A. Single episode fully resolvedIf the AME can determine the condition has fully resolved with no residual sequelae which would interfere with flight duties:Symbol: A. Single episode fully resolvedISSUESummarize findings in Item 60.
B. All others• Currently on antibiotics• 2 or more lifetime episodes• Chronic or recurrent infection• Functional limitation or required amputationSubmit the following for FAA review:1. A current, detailed Clinical Progress Note generated from a clinic visit with an infectious disease specialist or treating physician no more than 90 days before the AME exam.It should include a summary of the history of the condition or diagnosis; current medications, dosages, and side effects (if any); clinical exam findings; results of any testing performed; diagnosis; assessment and plan (prognosis); and follow-up.2. It must specifically include:• Etiology or any underlying cause with frequency of episodes (chronic or recurrent) and likelihood to reoccur.• Any functional limitations.Symbol: B. All others
• Currently on antibiotics
• 2 or more lifetime episodes
• Chronic or recurrent infection
• Functional limitation or required amputationDEFERSubmit the information to the FAA for a possible Special Issuance.Summarize findings in Item 60.If not addressed in the progress note, the AME should describe any functional limitations that could affect the pilot's ability to operate aircraft controls.
  • UPPER AND LOWER EXTREMITIES
  • All Classes
  • (Updated 08/26/2026)
DISEASE/CONDITIONEVALUATION DATADISPOSITION
AmputationsSubmit a current, detailed Clinical Progress Note to include functional status (degree of impairment as measured by strength, range of motion, pain), medications with side effects (if any), and all pertinent medical reportsIf applicant has a SODA issued on the basis of the amputation - IssueOtherwise - Requires FAA Decision After review of all medical data, the FAA may authorize a special medical flight test
Atrophy of any muscles that is progressive,Deformities, either congenital or acquiredORLimitation of motion of a major joint, that are sufficient to interfere with the performance of pilot dutiesSubmit a current, detailed Clinical Progress Note to include functional status (degree of impairment as measured by strength, range of motion, pain), medications with side effects (if any), and all pertinent medical reportsRequires FAA Decision
NeuralgiaSee Item 46. Neurologic, Other Conditions - Neuralgia (Trigeminal Neuralgia, Post Herpetic Neuralgia) Disposition TableSee disposition table
Sciatica, if sufficient to interfere with function or is likely to become incapacitatingSubmit a current, detailed Clinical Progress Note to include functional status (degree of impairment as measured by strength, range of motion, pain), medications with side effects (if any), and all pertinent medical reportsRequires FAA Decision
TremorSee Item 46. Neurologic, Extrapyramidal, Hereditary, and Degenerative Diseases of the Nervous System- Tremor Disposition TableSee disposition table
  • Item 43. Spine, Other Musculoskeletal
  • ARTHRITIS
  • All Classes
  • (Updated 04/29/2026)
DISEASE/CONDITIONEVALUATION DATADISPOSITION
A. Osteoarthritis• Well controlled, no persistent daily symptoms;• No functional limitations; and• Treatment is NSAIDS or antiinflammatory medication only.Symbol: A. OsteoarthritisISSUESummarize this History, annotate Block 60.
B. Osteoarthritis on additional medicationORAutoimmune arthritisSee CACI worksheetThis will require a current, detailed clinical progress noteand Hydroxychloroquine (HCQ)/ Chloroquine (CQ) Status Summary (Plaquenil/Aralen) if taking plaquenil.Follow the CACI - Arthritis WorksheetAnnotate Block 60.
C. All others• Complications*;• Symptomatic; or• Underlying cause with complications or systemic disease, etc.Submit the following to the FAA for review:☐ A current, detailed Clinical Progress Note generated from a clinic visit with the treating physician no more than 90 days before the AME exam. It must include a detailed summary of the history of the condition; current medications, dosage, and side effects (if any); physical exam findings; results of any testing performed; diagnosis; assessment; plan (prognosis); and follow-up. ☐ It should note if there are any functional limitations. ☐ Operative notes (if applicable); and ☐ Copies of imaging reports and lab (if already performed by treating physician)Symbol: C. All others
• Complications*;
• Symptomatic; or
• Underlying cause with complications or systemic disease, etc.DEFERSubmit the information to the FAA for a possible Special Issuance.Follow up Issuance Will be per the airman’s authorization letter.

*Complications include:

Joint deformity or decreased range of motion or strength that would impair flight duties

Systemic disease

CACI - Arthritis Worksheet (Updated 04/29/2026)

To determine the applicant’s eligibility for certification, the AME must review a current, detailed Clinical Progress Note generated from a clinic visit with the treating physician or specialist no more than 90 days prior to the AME exam. If the applicant meets ALL the acceptable certification criteria listed below, the AME can issue. Applicants for first- or second- class must provide this information annually; applicants for third-class must provide the information with each required exam.

AME MUST REVIEWACCEPTABLE CERTIFICATION CRITERIA
Treating physician finds the condition stable on current regimen and no changes recommended[ ] Yes
Symptoms[ ] None or mild to moderate symptoms with no significant limitations to range of motion, lifestyle, or activities
Cause of Arthritis*Osteoarthritis - see Arthritis Disposition Table CACI may not be required.Acceptable causes are limited to: [ ] Osteoarthritis* and/or [ ] Autoimmune to include only the following: rheumatoid (limited to joint), psoriatic, or ankylosing spondylitis
Acceptable MedicationsKEY:Interleukin Inhibitors (IL)Janus Associated Kinase Inhibitor (JAK)Monoclonal Antibody, Anti-CD20 (CD20)Phosphodiesterase-4 Enzyme Inhibitor (PDE4)Selective T-Cell Costimulation Blocker (T-Cell)Tumor necrosis factor inhibitors (TNF)[ ] One or more of the following with or without routine NSAID use:• Oral steroid prednisone 20 mg/day equivalent or less (see steroid conversion calculator)• NSAID (routine use)• azathioprine (Imuran)• methotrexate (Trexall)• sulfasalazine (Azulfidine)• Hydroxychloroquine (HCQ)/Chloroquine (Plaquenil/Aralen) see status report requirement below**• Any singe medication listed below after a 2-week ground trial and:▪ No post-dose observation time: o PDE4: apremilast (Otezla) o JAK: baricitinib (Olumiant); tofacitinib (Xeljanz); upadacitinib (Rinvoq)▪ 4-hour post-dose observation time: o TNF: adalimumab (Humira and all biosimilars), certolizumab (Cimzia), etanercept (Enbrel), golimumab (Simponi) o IL: anakinra (Kineret), guselkumab (Tremfya), ixekizumab (Taltz), risankizumab (Skyrizi), sarilumab (Kevzara), secukinumab (Cosentyx), tocilizumab (Actemra), ustekinumab (Stelara)▪ Other post-dose observation time: o 72-hour rituximab (Rituxan) 72-hour - CD20 o 24 hours: infliximab (Inflect, Remicade, Renflexis) - TNF o 24 hours: abatacept (Orencia) – T-Cell
** STATUS SUMMARY is required if Hydroxychloroquine (HCQ)/Chloroquine (CQ) (Plaquenil/Aralen) is used.[ ] Hydroxychloroquine (HCQ)/ Chloroquine (CQ) Status Summary (Plaquenil/Aralen) is favorable and no concerns OR [ ] N/A (NOT taking hydroxychloroquine/chloroquine [Plaquenil/Aralen])

AME MUST NOTE in Block 60 one of the following:

[ ] CACI qualified arthritis. (Documents do not need to be submitted to the FAA.) [ ] Has current OR previous SI/AASI but now CACI qualified arthritis. [ ] NOT CACI qualified arthritis. I have deferred. (Submit supporting documents.)

  • CEREBRAL PALSY
  • All Classes
  • (Updated 01/25/2023)
DISEASE/CONDITIONEVALUATION DATADISPOSITION
A. Any historySubmit the following for FAA review:1. A current, detailed neurological evaluation, in accordance with the FAA Specifications for Neurologic Evaluation, generated from a clinic visit with the treating neurologist no more than 90 days before the AME exam.2. It must include and evaluation of items such as balance, strength, range of motion limitations and pain. It must describe any functional deficits or limitations for both large and small muscle groups as well as dexterity to operate an aircraft.3. All school/academic records: Educational accommodations, Individual Education Plan (IEP) such as a "504" plan, educational support services provided, educational assessments and testing associated with IEP or individualized accommodations, neuropsychological assessments and testing, educational transcripts, and, if available, chief pilot reports.Note: In some cases, additional information such as brain imaging (MRI/CT) or neurocognitive testing may be required after review of the above items.Physical limitations associated with CP may require a Medical Flight Test (MFT). If a MFT is required, please state which FSDO the individual would prefer to use.Symbol: A. Any historyDEFERSubmit the information to the FAA for a possible Special Issuance.
  • COLLAGEN DISEASE
  • All Classes
  • (Updated 03/29/2023)
DISEASE/CONDITIONEVALUATION DATADISPOSITION
Acute Polymyositis; Dermatomyositis; Lupus Erythematosus; or Polyarteritis NodosaSubmit a current, detailed Clinical Progress Note generated from a clinic visit with the treating physician no more than 90 days before the AME exam. It must include a detailed summary of the history of the condition; current medications, dosage, and side effects (if any); physical exam findings; results of any testing performed; diagnosis; assessment; plan (prognosis); and followup.Requires FAA Decision
  • GOUT AND PSEUDOGOUT
  • All Classes
  • (Updated 04/29/2015)
DISEASE/CONDITIONEVALUATION DATADISPOSITION
Gout PseudogoutWell controlledInterview and examination reveal:☐ No persistent symptoms or functional impairment.☐ Med combinations of NSAIDS, uric acid reducers (allopurinol, etc.), or uric acid excreters (probenecid) with no aeromedically significant side effects.Symbol: Gout Pseudogout
Well controlledISSUE Note findings in Block 60.
Gout PseudogoutFunctional impairment Joint deformity Kidney stones, recurrent Meds other than above Not controlled Persistent symptomsSubmit a current, detailed Clinical Progress Note generated from a clinic visit with the treating physician no more than 90 days before the AME exam. It must include a detailed summary of the history of the condition; current medications, dosage, and side effects (if any); physical exam findings; results of any testing performed; diagnosis; assessment; plan (prognosis); and followup. It should also address:☐ Severity and frequency of exacerbations to include interval between and date of most recent flare; ☐ Extent of renal involvement; and ☐ Extent of joint deformity or functional impairment and if it would impair operation of aircraft controls.Symbol: Gout Pseudogout
Functional impairment Joint deformity Kidney stones, recurrent Meds other than above Not controlled Persistent symptomsDEFER Submit records to the FAA for decisionFollow up - per SI/AASI
  • SPINE, OTHER MUSCULOSKELETAL
  • All Classes
  • (Updated 03/29/2023)
DISEASE/CONDITIONEVALUATION DATADISPOSITION
Active disease of bones and jointsIf due to a specific condition – See those pagesIf due to arthritis – See the Arthritis pageSubmit a current, detailed Clinical Progress Note generated from a clinic visit with the treating physician no more than 90 days before the AME exam. It must include a detailed summary of the history of the condition; current medications, dosage, and side effects (if any); physical exam findings; results of any testing performed; diagnosis; assessment; plan (prognosis); and follow-up.Include functional status (degree of impairment as measured by strength, range of motion, pain).Requires FAA Decision
Ankylosis, curvature, or other marked deformity of the spinal column sufficient to interfere with the performance of pilot dutiesSubmit a current, detailed Clinical Progress Note generated from a clinic visit with the treating physician no more than 90 days before the AME exam. It must include a detailed summary of the history of the condition; current medications, dosage, and side effects (if any); physical exam findings; results of any testing performed; diagnosis; assessment; plan (prognosis); and follow-up.Include functional status (degree of impairment as measured by strength, range of motion, pain).Requires FAA Decision
Intervertebral Disc SurgerySee noteSee note
Musculoskeletal effects of:Muscular DystrophyOrMyopathiesSubmit a current, detailed Clinical Progress Note generated from a clinic visit with the treating physician no more than 90 days before the AME exam. It must include a detailed summary of the history of the condition; current medications, dosage, and side effects (if any); physical exam findings; results of any testing performed; diagnosis; assessment; plan (prognosis); and follow-up.Requires FAA Decision
Include functional status (degree of impairment as measured by strength, range of motion, pain).
Musculoskeletal effect of Myasthenia GravisSee Myasthenia Gravis Disposition TableSee disposition table
Other disturbances of musculoskeletal function, acquired or congenital, sufficient to interfere with the performance of pilot duties or likely to progress to that degreeSubmit a current, detailed Clinical Progress Note generated from a clinic visit with the treating physician no more than 90 days before the AME exam. It must include a detailed summary of the history of the condition; current medications, dosage, and side effects (if any); physical exam findings; results of any testing performed; diagnosis; assessment; plan (prognosis); and follow-up.Include functional status (degree of impairment as measured by strength, range of motion, pain).Requires FAA Decision
Symptomatic herniation of intervertebral discSubmit a current, detailed Clinical Progress Note generated from a clinic visit with the treating physician no more than 90 days before the AME exam. It must include a detailed summary of the history of the condition; current medications, dosage, and side effects (if any); physical exam findings; results of any testing performed; diagnosis; assessment; plan (prognosis); and follow-up.Include functional status (degree of impairment as measured by strength, range of motion, pain).Requires FAA Decision

Note: A history of intervertebral disc surgery is not disqualifying. If the applicant is asymptomatic, has completely recovered from surgery, is taking no medication, and has suffered no neurological deficit, the AME should confirm these facts in a brief statement in Block 60. The AME may then issue any class of medical certificate, providing that the individual meets all the medical standards for that class.

The paraplegic whose paralysis is not the result of a progressive disease process is considered in much the same manner as an amputee. The AME should defer issuance and may advise the applicant to request a Medical Flight Test. Other neuromuscular conditions are covered in more detail in Item 46.

Regulations Referenced in This Chapter

14 CFR 67.113
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